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1

Inhibition of hepatitis C virus replication by chloroquine targeting virus-associated autophagy

Tomokazu Mizui, Shunhei Yamashina, Isei Tanida, Yoshiyuki Takei, Takashi Ueno, Naoya Sakamoto, Kenichi Ikejima, Tsuneo Kitamura, Nobuyuki Enomoto, Tatsuo Sakai, Eiki Kominami, Sumio Watanabe

Journal:

Journal of Gastroenterology

Year:

2010

Language:

english

File:

PDF, 378 KB

english, 2010

2

Autophagy and Neurodegeneration

Komatsu, Masaaki, Kominami, Eiki, Tanaka, Keiji

Journal:

Year:

2006

Language:

english

File:

PDF, 466 KB

english, 2006

3

Loss of autophagy in the central nervous system causes neurodegeneration in mice

Komatsu, Masaaki, Waguri, Satoshi, Chiba, Tomoki, Murata, Shigeo, Iwata, Jun-ichi, Tanida, Isei, Ueno, Takashi, Koike, Masato, Uchiyama, Yasuo, Kominami, Eiki

Journal:

Year:

2006

Language:

english

File:

PDF, 521 KB

english, 2006

4

Genornic Structure of Human Cystatin A

Yamazakf, Masashi, Ishidoh, Kazumi, Kominami, Eiki, Ogawa, Hideoki

Journal:

Mitochondrial DNA

Year:

1997

Language:

english

File:

PDF, 520 KB

english, 1997

5

Inhibitory Effect of di- and Tripeptidyl Aldehydes on Calpains and Cathepsins

Sasaki, Takashi, Kishi, Motoharu, Saito, Masayuki, Tanaka, Takaharu, Higuchi, Naoki, Kominami, Eiki, Katunuma, Nobuhiko, Murachi, Takashi

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

1990

Language:

english

File:

PDF, 468 KB

english, 1990

6

Impairment of Starvation-Induced and Constitutive Autophagy in Atg7-Deficient Mice

Masaaki Komatsu, Satoshi Waguri, Takashi Ueno, Junichi Iwata, Shigeo Murata, Isei Tanida, Junji Ezaki, Noboru Mizushima, Yoshinori Ohsumi, Yasuo Uchiyama, Eiki Kominami, Keiji Tanaka and Tomoki Chiba

Journal:

The Journal of Cell Biology

Year:

2005

Language:

english

File:

PDF, 3.22 MB

english, 2005

7

Changes in Subcellular Structures of Parietal Cells in the Rat Gastric Gland after Omeprazole.

FURUHASHI, Masako, NAKAHARA, Akira, FUKUTOMI, Hisayuki, KOMINAMI, Eiki, UCHIYAMA, Yasuo

Journal:

Archives of Histology and Cytology

Year:

1992

Language:

english

File:

PDF, 22.80 MB

english, 1992

8

The antigen presentation pathway in medullary thymic epithelial cells, but not that in cortical thymic epithelial cells, conforms to the endocytic pathway

Michiyuki Kasai, Eiki Kominami, Toshiaki Mizuochi

Journal:

European Journal of Immunology

Year:

1998

Language:

english

File:

PDF, 294 KB

english, 1998

9

CLIP-derived self peptides bound to MHC class II molecules of medullary thymic epithelial cells differ from those of cortical thymic epithelial cells in their diversity, length, and C-terminal processing

Michiyuki Kasai, Harald Kropshofer, Anne B. Vogt, Eiki Kominami, Toshiaki Mizuochi

Journal:

European Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 335 KB

english, 2000

10

Variations in immunoreactivity of angiotensinogen and cathepsins B and H in rat hepatocytes over 24 hours

Satoshi Waguri, Tsuyoshi Watanabe, Eiki Kominami, Yasuo Uchiyama

Journal:

Developmental Dynamics

Year:

1990

Language:

english

File:

PDF, 1.16 MB

english, 1990

11

Abnormal degradative pathway of mitochondrial ATP synthase subunit c in late infantile neuronal ceroid-lipofuscinosis (Batten disease)

Junji Ezaki, Leonhard S. Wolfe, Kazumi Ishidoh, Eiki Kominami

Journal:

American Journal of Medical Genetics Part A

Year:

1995

Language:

english

File:

PDF, 720 KB

english, 1995

12

Changes in immunoreactivity for cathepsin H in rat type II alveolar epithelial cells and its proteolytic activity in bronchoalveolar lavage fluid over 24 hours

Yukio Ishii, Yutaka Hashizume, Eiki Kominami, Yasuo Uchiyama

Journal:

The Anatomical Record Advances in Integrative Anatomy and Evolutionary Biology

Year:

1991

Language:

english

File:

PDF, 552 KB

english, 1991

13

Isolation of tryptic fragment of antigen from mitochondrial inner membrane proteins reacting with antimitochondrial antibody in sera of patients with primary biliary cirrhosis

Daisaku Muno, Eiki Kominami, Hideo Ishii, Koh Usui, Koji Saifuku, Yuji Sakakibara, Toshihiko Namihisa

Journal:

Year:

1990

Language:

english

File:

PDF, 814 KB

english, 1990

14

Sustained calpain activation associated with lysosomal rupture executes necrosis of the postischemic CA1 neurons in primates

Tetsumori Yamashima, Anton B. Tonchev, Toshiyuki Tsukada, Takaomi C. Saido, Shinobu Imajoh-Ohmi, Takashi Momoi, Eiki Kominami

Journal:

Year:

2003

Language:

english

File:

PDF, 713 KB

english, 2003

15

Peroxisome degradation in mammals

Junji Ezaki, Eiki Kominami, Takashi Ueno

Journal:

Year:

2011

Language:

english

File:

PDF, 1.31 MB

english, 2011

16

Immunohistochemical characterization of the intracellular pool of water channel aquaporin-2 in the rat kidney

Yuki Tajika, Toshiyuki Matsuzaki, Takeshi Suzuki, Takeo Aoki, Haruo Hagiwara, Shigeyasu Tanaka, Eiki Kominami, Kuniaki Takata

Journal:

Anatomical Science International

Year:

2002

Language:

english

File:

PDF, 3.62 MB

english, 2002

17

Cloning and characterization of two neural-salient serine/arginine-rich (NSSR) proteins involved in the regulation of alternative splicing in neurones

Masaaki Komatsu, Eiki Kominami, Kiichi Arahata, Toshifumi Tsukahara

Journal:

Year:

1999

Language:

english

File:

PDF, 448 KB

english, 1999

18

CLC-3 deficiency leads to phenotypes similar to human neuronal ceroid lipofuscinosis

Momono Yoshikawa, Shinichi Uchida, Junji Ezaki, Tatemitsu Rai, Atsushi Hayama, Katsuki Kobayashi, Yujiro Kida, Masaki Noda, Masato Koike, Yasuo Uchiyama, Fumiaki Marumo, Eiki Kominami, Sei Sasaki

Journal:

Year:

2002

Language:

english

File:

PDF, 274 KB

english, 2002

19

Immunohistochemical localization of lysosomal cysteine protease cathepsins B and L in monkey hippocampal neurons after transient ischemia

Yukihiko Kohda, Katsuhiro Tsuchiya, Junkoh Yamashita, Masaki Yoshida, Takashi Ueno, Tohru Yoshioka, Eiki Kominami, Tetsumori Yamashima

Journal:

Year:

1999

Language:

english

File:

PDF, 532 KB

english, 1999

20

Inhibition of ischaemic hippocampal neuronal death in primates with cathepsin B inhibitor CA-074: a novel strategy for neuroprotection based on ‘calpain–cathepsin hypothesis’

Tetsumori Yamashima, Yukihiko Kohda, Katsuhiro Tsuchiya, Takashi Ueno, Junkoh Yamashita, Tohru Yoshioka, Eiki Kominami

Journal:

European Journal of Neuroscience

Year:

1998

Language:

english

File:

PDF, 869 KB

english, 1998

21

Specific Delay of Degradation of Mitochondrial ATP Synthase Subunit c in Late Infantile Neuronal Ceroid Lipofuscinosis (Batten Disease)

Junji Ezaki, Leonhard S. Wolfe, Tomihiko Higuti, Kazumi Ishidoh, Eiki Kominami

Journal:

Journal of Neurochemistry

Year:

1995

Language:

english

File:

PDF, 1.15 MB

english, 1995

22

Specific Delay in the Degradation of Mitochondrial ATP Synthase Subunit c in Late Infantile Neuronal Ceroid Lipofuscinosis Is Derived from Cellular Proteolytic Dysfunction Rather than Structural Alteration of Subunit c

Junji Ezaki, Leonhard S. Wolfe, Eiki Kominami

Journal:

Journal of Neurochemistry

Year:

1996

Language:

english

File:

PDF, 1.53 MB

english, 1996

23

A Lysosomal Proteinase, the Late Infantile Neuronal Ceroid Lipofuscinosis Gene (CLN2) Product, Is Essential for Degradation of a Hydrophobic Protein, the Subunit c of ATP Synthase

Junji Ezaki, Isei Tanida, Nobuo Kanehagi, Eiki Kominami

Journal:

Journal of Neurochemistry

Year:

1999

Language:

english

File:

PDF, 290 KB

english, 1999

24

Characterization of Cln3p, the gene product responsible for juvenile neuronal ceroid lipofuscinosis, as a lysosomal integral membrane glycoprotein

Junji Ezaki, Mitsue Takeda-Ezaki, Masato Koike, Yoshiyuki Ohsawa, Hikari Taka, Reiko Mineki, Kimie Murayama, Yasuo Uchiyama, Takashi Ueno, Eiki Kominami

Journal:

Journal of Neurochemistry

Year:

2003

Language:

english

File:

PDF, 506 KB

english, 2003

25

Selective modulation of the secretion of proteinases and their inhibitors by growth factors in cultured differentiated podocytes

Asanuma, Katsuhiko, Shirato, Isao, Ishidoh, Kazumi, Kominami, Eiki, Tomino, Yasuhiko

Journal:

Kidney International

Year:

2002

Language:

english

File:

PDF, 2.97 MB

english, 2002

26

Muscle fiber degradation in distal myopathy with rimmed vacuoles

Toshihide Kumamoto, Hidetsugu Ueyama, Susumu Watanabe, Eiki Kominami, Masayuki Ando

Journal:

Acta Neuropathologica

Year:

1994

Language:

english

File:

PDF, 1.90 MB

english, 1994

27

Degradation of myelin proteins by cathepsin B and inhibition by E-64 analogue

Katsuhiko Yanagisawa, Shuzo Sato, Tadashi Miyatake, Eiki Kominami, Nobuhiko Katsunuma

Journal:

Neurochemical Research

Year:

1984

Language:

english

File:

PDF, 284 KB

english, 1984

28

Abnormal distribution of cathepsin proteinases and endogenous inhibitors (cystatins) in the hippocampus of patients with Alzheimer's disease, parkinsonism-dementia complex on Guam, and senile dementia and in the aged

Kunio Ii, Hidehumi Ito, Eiki Kominami, Asao Hirano

Journal:

Virchows Archiv

Year:

1993

Language:

english

File:

PDF, 2.10 MB

english, 1993

29

Primate neurons show different vulnerability to transient ischemia and response to cathepsin inhibition

Masaki Yoshida, Tetsumori Yamashima, Liang Zhao, Katsuhiro Tsuchiya, Yukihiko Kohda, Anton B. Tonchev, Masayuki Matsuda, Eiki Kominami

Journal:

Acta Neuropathologica

Year:

2002

Language:

english

File:

PDF, 297 KB

english, 2002

30

Accumulation of mitochondrial ATP synthase subunit c in muscle in a patient with neuronal ceroid lipofuscinosis (late infantile form)

F. Umehara, Itsuro Higuchi, Kenji Tanaka, Takahito Niiyama, Junji Ezaki, Eiki Kominami, Mitsuhiro Osame

Journal:

Acta Neuropathologica

Year:

1997

Language:

english

File:

PDF, 607 KB

english, 1997

31

Processing of cathepsins L, B and D in psoriatic epidermis

A. Kawada, Kenji Hara, Eiki Kominami, Masataro Hiruma, Hiromitsu Noguchi, Akira Ishibashi

Journal:

Archives of Dermatological Research

Year:

1997

Language:

english

File:

PDF, 468 KB

english, 1997

32

Expression of cathepsin

Celina M. Haraguchi, Kazuki Ishido, Eiki Kominami, Sadaki Yokota

Journal:

Histochemistry and Cell Biology

Year:

2003

Language:

english

File:

PDF, 574 KB

english, 2003

33

Hepatic gap junctions in the hepatocarcinogen-resistant DRH rat

Takahiro Gotow, Motoko Shiozaki, Taneaki Higashi, Kentaro Yoshimura, Masahiro Shibata, Eiki Kominami, Yasuo Uchiyama

Journal:

Histochemistry and Cell Biology

Year:

2008

Language:

english

File:

PDF, 906 KB

english, 2008

34

Both cathepsin B and cathepsin D are necessary for processing of ovalbumin as well as for degradation of class II MHC invariant chain

Toshiaki Mizuochi, Sung-Tae Yee, Michiyuki Kasai, Terutaka Kakiuchi, Daisaku Muno, Eiki Kominami

Journal:

Immunology Letters

Year:

1994

Language:

english

File:

PDF, 343 KB

english, 1994

35

Atg8L/Apg8L is the fourth mammalian modifier of mammalian Atg8 conjugation mediated by human Atg4B, Atg7 and Atg3

Isei Tanida, Yu-shin Sou, Naoko Minematsu-Ikeguchi, Takashi Ueno, Eiki Kominami

Journal:

Year:

2006

Language:

english

File:

PDF, 418 KB

english, 2006

36

The Intracellular Location and Function Of Proteins Of Neuronal Ceroid Lipofuscinoses

Junji Ezaki, Eiki Kominami

Journal:

Brain Pathology

Year:

2004

Language:

english

File:

PDF, 202 KB

english, 2004

37

10.1038/35044114

Ohsumi, Yoshinori, Ichimura, Yoshinobu, Kirisako, Takayoshi, Takao, Toshifumi, Satomi, Yoshinori, Shimonishi, Yasutsugu, Ishihara, Naotada, Mizushima, Noboru, Tanida, Isei, Kominami, Eiki, Ohsumi, Mar

Journal:

Year:

2000

Language:

english

File:

PDF, 288 KB

english, 2000

38

A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier

Komatsu, Masaaki, Chiba, Tomoki, Tatsumi, Kanako, Iemura, Shun-ichiro, Tanida, Isei, Okazaki, Noriko, Ueno, Takashi, Kominami, Eiki, Natsume, Tohru, Tanaka, Keiji

Journal:

The EMBO Journal

Year:

2004

Language:

english

File:

PDF, 474 KB

english, 2004

39

Letter to the Editor:1H,13C, and15N Resonance Assignments of Human Microtubule-associated Protein Light Chain-3

Takahide Kouno, Mineyuki Mizuguchi, Isei Tanida, Takashi Ueno, Eiki Kominami, Keiichi Kawano

Journal:

Journal of Biomolecular NMR

Year:

2004

Language:

english

File:

PDF, 77 KB

english, 2004

40

Proenzyme Form of Cathepsin L Produced by Thymic Epithelial Cells Promotes Proliferation of Immature Thymocytes in the Presence of IL-1, IL-7, and Anti-CD3 Antibody

Michiyuki Kasai, Takuji Shirasawa, Masanori Kitamura, Kazumi Ishido, Eiki Kominami, Katsuiku Hirokawa

Journal:

Cellular Immunology

Year:

1993

File:

PDF, 638 KB

1993

41

Variations in immunocytochemical localization of cathepsin B and thyroxine in follicular cells of the rat thyroid gland and plasma TSH concentrations over 24 hours

Yasuo Uchiyama, Masahiko Watanabe, Tsuyoshi Watanabe, Yukio Ishii, Hisako Matsuba, Satoshi Waguri, Eiki Kominami

Journal:

Cell and Tissue Research

Year:

1989

Language:

english

File:

PDF, 804 KB

english, 1989

42

The substrate specificity of proteinase B from Baker's yeast

Eiki Kominami, Hedda Hoffschulte, Lieselotte Leuschel, Konrad Maier, Helmut Holzer

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Year:

1981

Language:

english

File:

PDF, 405 KB

english, 1981

43

Properties of fructose-1,6-bisphosphate aldolase inactivating enzymes in rat liver lysosomes

Eiki Kominami, Seiichi Hashida, Nobuhiko Katunuma

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Year:

1981

Language:

english

File:

PDF, 638 KB

english, 1981

44

Purification and properties of proteinase B from yeast

Eiki Kominami, Hedda Hoffschulte, Helmut Holzer

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Year:

1981

Language:

english

File:

PDF, 861 KB

english, 1981

45

Proteolytic modification of rat liver fructose-1,6-bisphosphate aldolase by administration of leupeptin in vivo

Eiki Kominami, Seiichi Hashida, Nobuhiko Katunuma

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Year:

1981

Language:

english

File:

PDF, 729 KB

english, 1981

46

Expression of Cysteine Proteinases and Their Inhibitor, Cystatin β, in Cultured Rat Mesangial Cells

Yuichiro Makita, Kazumi Ishidoh, Eiki Kominami, Kazuhiko Funabiki, Hikaru Koide, Yasuhiko Tomino

Journal:

Journal of Diabetes and its Complications

Year:

1998

Language:

english

File:

PDF, 287 KB

english, 1998

47

Human osteoarthritic cartilage exhibits the 2B6 epitope without pretreatment with chondroitinase ABC

Akira Asari, Shaw Akizuki, Tomomi Itoh, Eiki Kominami, Yasuo Uchiyama

Journal:

Osteoarthritis and Cartilage

Year:

1996

Language:

english

File:

PDF, 1.43 MB

english, 1996

48

Morphological studies on CLN2

Hans H. Goebel, Eiki Kominami, Eva Neuen-Jacob, Ruth B. Wheeler

Journal:

European Journal of Paediatric Neurology

Year:

2001

Language:

english

File:

PDF, 1.91 MB

english, 2001

49

Autophagy in embryonic erythroid cells: its role in maturation

Hiromi Takano-Ohmuro, Masahiro Mukaida, Eiki Kominami, Kiyokazu Morioka

Journal:

European Journal of Cell Biology

Year:

2000

Language:

english

File:

PDF, 623 KB

english, 2000

50

Myosin in hepatocytes is essential for bile canalicular contraction

Sumio Watanabe, Akihisa Miyazaki, Miyoko Hirose, Makoto Takeuchi, Hirosumi Ohide, Tsuneo Kitamura, Takasi Ueno, Eiki Kominami, Nobuhiro Sato

Journal:

Liver International

Year:

1991

Language:

english

File:

PDF, 392 KB

english, 1991